Typhidot Test (IgM & IgG): Get Price, Purpose & Results [2024]
The typhidot test is a blood test that helps detect the presence of IgG and IgM antibodies against typhoid-causing bacteria, Salmonella typhi. The immune system produces proteins known as antibodies in response to an infection, indicating exposure to the bacterium. The Typhidot test is effective for typhoid fever diagnosis. Typhoid fever is a bacterial infection that spreads through contaminated food & drinking water. It can also spread through close contact from one person to another. The disease mainly affects the intestinal tract, liver, and spleen. The price of this test ranges between Rs 350 to Rs 675 on average.
Your doctor may recommend a Typhidot test because of the following reasons:
- High fever, often over 103°F (39.4°C)
- Abdominal pain and cramps
- Loss of appetite and weight loss
- Headache and body aches
- Fatigue and weakness
- Diarrhea or constipation
- Rash of small, flat, rose-colored spots
- Enlarged liver and spleen
- Confusion or delirium (in severe cases)
Typhidot Test details in brief
| Also Known As | Typhoid IgM/IgG rapid test, Typhoid serology test, Rapid typhoid test, Typhoid Antibody Test |
| Purpose | To detect the presence of antibodies against Salmonella typhi in the blood, which can indicate a current or recent infection with typhoid fever. |
| Preparation | No special preparation is required. |
| Fasting | No |
| Reporting Time | <24 Hours |
| Cost | Rs 350 to Rs 675 |
Typhidot Test Price
The Typhidot Test Price usually ranges from Rs 350 to Rs 675. The actual price depends on the diagnostic centre and the city. Bookmerilab partners with more than 506 diagnostic centres across India. We provide a 10-50% discount on medical diagnostic tests.
Prices at Popular diagnostic centres
The table below lists the prices at some of the popular diagnostic centres.
| Name of Lab | Test Price |
|---|---|
| Redcliffe Labs | Rs 350 |
| Aarthi Scan | Rs 450- Rs 675 ( City-based ) |
| City X-Ray | Rs 675 |
| Bharat X-Ray | Rs 520 |
| Prognosis Laboratories | Rs 360 |
| Janta X-Ray Clinic | Rs 600 |
| Vijaya Diagnostics | Rs 500 |
| Dr Lal Pathlabs | Rs 450 |
Cost in different cities
The test cost depends upon the one recommended by your healthcare professional. The table below gives the combined cost of the Typhidot IgM and IgG test. In case, you have been recommended only IgM, then the cost will be lower. The cost varies depending on the lab and the city.
| City | Test Price |
|---|---|
| Typhidot Test Price in Delhi | Rs 350 to Rs 675 |
| Typhidot Test Price in Mumbai | Rs 350 to Rs 665 |
| Typhidot Test Price in Bangalore | Rs 350 to Rs 450 |
| Typhidot Test Price in Hyderabad | Rs 350 to Rs 780 |
| Typhidot Test Price in Gurgaon | Rs 328 to Rs 572 |
| Typhidot Test Price in Chennai | Rs 350 to Rs 675 |
| Typhidot Test Price in Kolkata | Rs 350 |
Typhidot Test Purpose
Your doctor may recommend a Typhidot IgM test to detect a recent infection or IgG for past infection of Typhoid.
- Healthcare professionals use the test to diagnose typhoid fever and determine if the Salmonella typhi bacteria are present in a person’s blood sample.
- The test can identify early disease instances, which are challenging to identify using standard laboratory techniques.
- It can be used to screen people who are at a high risk of contracting typhoid fever, such as those who have just returned from a trip to a region where the illness is widespread or who have recently come in contact with infected people.
- The test can be used to evaluate a patient’s reaction to typhoid fever treatment and establish whether the treatment is effective.
Preparation
It does not require fasting or any special preparations. It is crucial to let the doctor know if you have a bleeding issue or are using blood-thinning drugs because the test requires collecting a small sample of blood from a vein in the arm. Also, let your doctor know about any vitamins, drugs, or herbal remedies you’re using because some of them may alter how accurately the test results come back. It is important to inform the healthcare provider if the person has any medical conditions that may affect the test results. The healthcare provider may provide additional instructions specific to the patient.
Procedure
It is a fairly simple diagnostic blood test. Below are the steps to draw a blood sample from the vein in your arm or hand-
- A technician (phlebotomist) may tie a tourniquet (elastic band) to your arm.
- The phlebotomist will locate your blood vessel.
- Then the site is cleaned with spirit.
- A Needle is inserted into your vein to draw the blood.
- The blood sample is then withdrawn into a syringe or a vial.
- Cotton is placed on the puncture site with mild pressure till the bleeding stops.
- A small band-aid is then placed, which may be removed after an hour.
The entire procedure takes only a few minutes.
Risks
It is a very simple and safe test. The risks involved are the same as that of any other blood test. These include-
- Infection at the puncture site if proper sterilization protocol is not followed and the needle is contaminated. This is, however, very rare. You may ensure that your phlebotomist takes out the needle in front of you from a sterile pack.
- Multiple pricks if the blood vessel is not easily found
- Excessive bleeding at the puncture site- Please inform your healthcare provider if you are taking any blood thinners or have any bleeding disorders.
- Light-headedness due to stress or heavy bleeding.
Minor pain and bruising that might occur will resolve on their own in a very short time.
Results
When testing for typhoid antibodies, healthcare providers may look for both IgM and IgG antibodies in the blood. The presence of IgM antibodies indicates a recent or active infection. The presence of IgG antibodies suggests either a past infection or vaccination.
The patient’s serum is mixed with an antigen containing fragments of the Salmonella Typhi bacterium, and if there are antibodies present they will bind to the antigens and create visible spots on the slide. These spots can then be counted and measured for a result. Typically, the Typhidot test yields positive or negative results.
The detection of antibodies to Salmonella typhi in the blood indicates a recent or active case of typhoid fever, which is signified by a positive test result.
A negative test result indicates the absence of detected antibodies. This means that the subject is not infected with typhoid fever or that the sample was taken too early for antibodies to develop.
Sample Report
Limitations
While this test can be helpful in diagnosing the disease, it has some limitations, including:
- False positives: It can produce false positive results if the patient has been vaccinated against Salmonella typhi or has been exposed to other bacteria that elicit similar antibodies.
- Limited sensitivity: The test may not detect antibodies in the early stages of the infection. Hence, a negative result does not rule out the possibility of typhoid fever.
- Limited specificity: The test may also produce false negative results if the patient has recently been infected but has not yet produced detectable antibodies.
- Inconclusive results: Sometimes the test may produce inconclusive results, which may require further testing to confirm the diagnosis.
Conclusion
Healthcare professionals use this test as a valuable diagnostic tool for identifying Salmonella typhi infection, especially in regions where the disease is prevalent. This test detects IgM & IgG antibodies, the markers of exposure to typhoid bacteria. It is relatively simple, safe, and fast, with results usually available within a few hours. Individuals who are at risk of typhoid fever or who experience symptoms of the disease should consult with a healthcare provider to determine if a Typhi dot test or other diagnostic tests are necessary. Overall, the typhidot test is useful in diagnosing typhoid fever, but its interpretation has to be in conjunction with other clinical and laboratory findings.
FAQs
It is a blood test used to diagnose typhoid fever.
A blood sample is collected from the person and applied to a test strip containing specific antibodies.
It indicates the presence of antibodies against the Salmonella typhi bacteria.
It may mean that the person does not have typhoid fever, but false-negative results are possible.
It has relatively high sensitivity and specificity, but false-positive and false-negative results can occur.
People who are at risk of typhoid fever or who experience symptoms of the disease may be recommended to have the test.
The person may be asked to fast for a certain period before the test.
The risks are minimal, but pain, discomfort, or bruising at the site of blood collection are possible.
Results are usually available within a few hours of sample collection.
Yes, it can be used to monitor a person’s response to treatment for typhoid fever.
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Dr Garima Saroj
Dr Garima Saroj is a dentist from Manipal college of dental sciences. She has previously worked at ESIC dental college and hospital Delhi and Dentecare multispecialty dental clinic Gurugram. She has a passion for writing for patient education and awareness.