ACE Test: Price, Purpose, Preparation & Results [2024]

• Price
• Purpose
• Preparation
• Procedure
• Results
• Sample Report

What is the serum ACE test? 

The ACE test measures how much angiotensin-converting enzyme is present in your blood. The test helps to diagnose and monitor a condition called sarcoidosis. Sarcoidosis is a systemic disorder (affecting the entire body) of unknown cause that often affects the lungs. It may also affect other body organs including the eyes, skin, lymph nodes, nerves, liver, spleen, and heart. The ACE Test Price usually ranges from Rs 900 to Rs 1200 and in-home sample collection may be availed.

What is the role of angiotensin-converting enzyme in your body? 

ACE is an enzyme that helps to convert angiotensin I into angiotensin II. This angiotensin II helps increase blood pressure by causing the small blood vessels in the body to narrow down. Thus, it helps control blood pressure.

ACE Test details in brief

Also Known As	Serum angiotensin-converting enzyme test, SACE Test
Purpose	Diagnosis and monitoring of sarcoidosis
Preparation	Overnight fasting is preferred
Fasting	Yes
Reporting Time	8 to 24 Hrs.
Cost	Rs. 900 to Rs. 1200

ACE Test Price

The ACE Test Price usually ranges from Rs 900 to Rs 1200. The actual price depends on the diagnostic center and the city. Bookmerilab partners with more than 200 diagnostic centers across India. We provide a 10-50% discount on medical diagnostic tests.

Price at Popular Diagnostic Centres

The table below lists the ACE prices at a few popular diagnostic centers.

Name of Lab	Test Price
Redcliffe Labs	Rs 1000
Dr Lal Path labs	Rs 1000
Thyrocare	Rs 600
Metropolis Healthcare	Rs 1100
SRL Diagnostics	Rs 1200
Vijaya Diagnostics	Rs 1200

Cost in different cities

The table below lists the prices in different cities. You can click on the name of the city to get the list of diagnostic centres with their price and discount.

City	Test Price
Delhi	Rs 750 to Rs 1300
Mumbai	Rs 1100 to Rs 1500
Bangalore	Rs 1300 to Rs 1500
Hyderabad	Rs 600 to Rs 1500
Gurgaon	Rs 1100 to Rs 1200
Chennai	Rs 1300 to Rs 1500
Kolkata	Rs 1000 to Rs 1200

What is the purpose of the ACE Test?

Angiotensin-converting enzyme (ACE) Test may be ordered by your doctor mainly for

• Diagnosis of sarcoidosis
• Monitoring the course of sarcoidosis and the effectiveness of corticosteroid therapy
• It helps to distinguish sarcoidosis from other systemic disorders having similar symptoms

Some symptoms of high ACE levels are-

People with sarcoidosis or high ACE level may show the following symptoms:

• Development of granulomas (tumor-like masses of immune cells and fibrous tissue) under the skin and other body organs
• Chronic (long-term) cough or shortness of breath
• Joint pain and stiffness
• Red, watery Eyes
• Fever and headache
• Extreme tiredness
• Dry mouth
• Unexplained weight loss and loss of appetite
• Unusual skin changes like rashes, etc. 

ACE Test Preparation

Overnight fasting is preferred for the ACE test.

Do inform your doctor if you are taking any medicine both prescription and non-prescription, ayurvedic, etc. Your doctor may advise you to stop the ones that can affect the test results like antihypertensives ( drugs used for high BP). DO NOT stop any medication on your own.

ACE Test Procedure

It is a fairly simple diagnostic blood test. A blood sample is taken from the vein in your arm or hand by the following steps-

1. A technician (phlebotomist) may tie a tourniquet (elastic band) to your arm.
2. The phlebotomist will locate your blood vessel.
3. The site is cleaned with spirit.
4. A Needle is inserted into your vein to draw the blood.
5. A blood sample is then withdrawn into a syringe or a vial.
6. Cotton is placed on the puncture site with mild pressure till the bleeding stops.
7. A small band-aid is then placed which may be removed after an hour.

The entire procedure takes only a few minutes.

Risks

It is a very simple and safe test. The risks involved are the same as that of any other blood test. These include-

• Infection at the puncture site if proper sterilization protocol is not followed and the needle is contaminated. This is, however, very rare. You may ensure that your phlebotomist takes out the needle in front of you from a sterile pack.
• Multiple pricks if the blood vessel is not easily found
• Excessive bleeding at the puncture site- Please inform your healthcare provider if you are taking any blood thinners or have any bleeding disorders.
• Light-headedness due to stress or heavy bleeding.

Minor pain and bruising that might occur will resolve on their own in a very short time.

Results and Interpretation 

Have a look at the table below for the range of angiotensin-converting enzymes.

Normal Levels

The normal range of angiotensin-converting enzymes is between 8 to 52 units per liter. 

Parameter	Range	Unit
Angiotensin-converting enzyme(ACE)	8.00-52.00	U/L

Please note- 

Sometimes deviation in ACE levels may also be seen in individuals due to the following factors-

• Smoking– ACE activity is lower in smokers by 30%.
• Thyroid hormone – stimulates the ACE synthesis
• ACE activity is 20% lower in patients undergoing post-menopausal estrogen replacement
• Patients taking medications like ACE inhibitors such as enalapril, captopril, etc will have very low ACE Levels 

Abnormal Levels

Higher Values

Increased levels of ACE may be found in-

• Sarcoidosis– ACE levels are used in the diagnosis and monitoring of this systemic illness. Mature granulomas produce less ACE than developing ones.
• Lung-related (Pulmonary) causes like asthma, emphysema, small cell carcinoma, and squamous cell carcinoma
• Kidney-related (Renal) diseases – higher ACE levels are seen in patients undergoing hemodialysis
• Gaucher’s disease (inherited condition in which fat accumulates in the liver, spleen, and bone marrow causing pain, bone damage, and even death) 
• Hodgkin’s lymphoma (cancer of lymph tissue)
• Multiple sclerosis ( a condition affecting the brain and the spinal cord with symptoms that cause problems with vision, limb movement, etc.) 
• Hyperthyroidism ( increased levels of thyroid hormone) 
• Addison’s disease (decreased cortisol levels causing symptoms like abdominal pain, weakness, weight loss, nausea, etc) 
• Alcoholic hepatitis (liver inflammation due to chronic consumption of alcohol) 
• Peptic ulcers ( ulcers in the lining of the stomach or duodenum, which is a part of the small intestine) 

Lower values

Decrease levels of ACE may be seen in

• Chronic liver disease
• Anorexia nervosa (an eating disorder characterized by fear of gaining weight, thinness, food restriction, etc. ) 
• Hypothyroidism ( low levels of thyroid hormone) 

Sample Report

Limitations

ACE levels will be higher in 50 to 80% of individuals with active sarcoidosis. However, normal ACE levels cannot be used to rule out sarcoidosis because it may be present without an elevated ACE level if the disease is in an inactive state or the cells do not produce an increased amount of ACE. ACE may also be normal in cases of chronic sarcoidosis.

Conclusion

The measure of Angiotensin-converting enzyme levels will help your doctor diagnose and monitor systemic diseases like sarcoidosis and Gaucher’s disease. It can also indicate other disorders but more tests may be needed for their diagnosis. Regardless of the results, it is essential for you to discuss them with your healthcare provider for a better understanding and course of action. 

 Exercise, meditate, breathe, and sleep well! We wish you a happy, healthy, and relaxed life! 

FAQs

Sources

ACE blood test Information | Mount Sinai – New York

ACE blood test | Canoe.Com

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